Chemical methods for detecting phycotoxins: LC and LC/MS/MS
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Phycotoxins are natural products which are generally synthesized by marine microalgae, especially those belonging to the dinoflagellates group. Approximately 20 species of dinoflagellates and a smaller number of diatoms are currently known to produce phycotoxins and these account for less than 2% of all microalgae species. They are known to produce intoxication syndromes thr oughout the food chain from tropical to polar latitudes (Hallegraeff, 1993). Marine biotoxins are non-proteinaceous compounds with vastly differing structures, whose mol ecular weights lie between 250-3500 daltons. Their physico-chemical proper ties vary according to thei r polarity, lipophylic nature, thermal stability, sensitivity to pH, oxygen and light, etc. Danger of biotoxins poisoning for humans lies in their acute and chro nic effects. Consum ption of seafood contaminated with marine biotoxins may cause serious diseases that affect: the nervous system in ...
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